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Coccidioides antibody serology (qualitative or quantitative, serum/plasma)

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies to *Coccidioides* fungi, which can cause infections like Valley Fever. It helps diagnose or monitor exposure to this fungus.

Quick summary

["This test checks for immune response to *Coccidioides* infection, often used in high-risk areas."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
93226-9
Short code
Coccidioides Ag SerPl IA-mCnc
Synonyms
Coccidioides Ag SerPl IA-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test if you live in or have traveled to regions with high risk of *Coccidioides* exposure (e.g., southwestern U.S., parts of Central/South America). It may also be used to evaluate symptoms like fever, cough, or skin rashes that could indicate infection.

What Does a Positive Result Mean?

A positive result suggests your immune system has recognized *Coccidioides* antigens, possibly indicating past or current infection. However, false positives can occur, so further evaluation may be needed.

What Does a Negative Result Mean?

A negative result means no detectable antibodies were found in your sample at this time. It does not definitively rule out infection, especially if symptoms persist or you have high exposure risk.

How Is the Test Performed?

A blood sample is drawn from a vein in your arm. The serum or plasma is then tested for antibodies using immunoassay methods (e.g., enzyme-linked immunosorbent assay, or ELISA). Results are qualitative (positive/negative) or quantitative (measured concentration).

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Coccidioides antibody test

Frequently asked questions

What are the common symptoms of *Coccidioides* infection?
Symptoms may include fever, cough, chest pain, fatigue, or skin rashes. Some people experience no symptoms at all, even if infected.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on lab processing times. Follow-up with your doctor if you have questions about your results.
Can I take anything special before this test?
No special preparations are needed. However, inform your doctor about any medications, including supplements, as they may affect test results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy