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Coccidioides antibody (IgG) – Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of antibodies in your blood that your immune system produces in response to *Coccidioides* fungi, a type of yeast-like fungus found in certain desert regions. It helps diagnose infections caused by this fungus, which can affect the lungs and other parts of the body.

Quick summary

["This test helps doctors determine if you have been exposed to or infected with *Coccidioides* fungi."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
46181-4
Short code
Coccidioides IgA Ser Ql
Synonyms
Coccidioides IgA Ser Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test detects IgG antibodies, which are part of your immune system’s response to *Coccidioides*. These antibodies develop after your body has been exposed to the fungus, often weeks or months after infection. IgG antibodies are typically present in people who have had an infection in the past or are currently fighting an active infection.

Why Might Your Doctor Order This Test?

Your doctor may recommend this test if you have symptoms like coughing, fever, chest pain, or fatigue, especially if you live in or have traveled to areas where *Coccidioides* is common. It may also be used to monitor treatment progress or check for past exposure in people with a history of risk factors, such as weakened immune systems or certain occupations.

How Is the Test Performed?

A blood sample is drawn from a vein in your arm. The sample is sent to a lab, where it is tested using an immunoassay method to detect IgG antibodies against *Coccidioides*. The results are compared to a standard to determine antibody levels.

What Are Possible Results?

Results can vary depending on the test sensitivity and your medical history. A positive result indicates the presence of IgG antibodies, suggesting past or current exposure to *Coccidioides*. A negative result means no detectable antibodies were found in this sample, but this does not rule out infection in all cases.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

IgG Antibody to Coccidioides

Frequently asked questions

What Does a Positive Result Mean?
A positive IgG antibody result suggests you have been exposed to *Coccidioides* fungi. This could mean you have an active infection, a past infection, or chronic infection. It is important to discuss your symptoms, medical history, and risk factors with your doctor to determine the next steps, such as further testing or treatment.
What Does a Negative Result Mean?
A negative result means no IgG antibodies were detected in this sample. However, this does not definitively rule out infection. Some people may not develop detectable antibodies, or the test may need to be repeated if symptoms persist or if there is suspicion of infection.
Can This Test Be Used to Monitor Treatment?
Yes, this test can be used to monitor treatment progress or assess long-term exposure. If you are receiving treatment for a *Coccidioides* infection, your doctor may order this test periodically to check for changes in antibody levels, which can help guide treatment decisions.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy