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Coccidioides antibody serology (IgG and IgA) by immunoassay

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies to *Coccidioides*, a fungus found in certain desert regions that can cause infections called coccidioidomycosis. Antibodies may appear after exposure or infection.

Quick summary

["Detects past or current exposure to the fungus *Coccidioides*, which can cause lung infections or other health issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
44811-8
Short code
Coccidioides IgA Ser Ql IA
Synonyms
Coccidioides IgA Ser Ql IA
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test measures two types of antibodies—IgG and IgA—that the body produces in response to *Coccidioides* exposure. IgG antibodies typically develop later and indicate past or ongoing infection, while IgA may appear in early or active infection phases.

Why Might You Need This Test?

Your doctor may order this test if you live in or have traveled to areas with high risk for *Coccidioides* (e.g., southwestern U.S., parts of Latin America), have symptoms like cough, fever, or fatigue, or if you have a weakened immune system.

What to Expect Before the Test

No special preparation is needed. A blood sample is drawn from a vein in your arm. The sample is sent to a lab for antibody testing.

What the Results Mean

Results are qualitative (positive/negative) rather than numeric. A positive result suggests past or current exposure/infection, but it does not confirm active disease without clinical correlation. Follow-up testing or evaluation by a healthcare provider may be needed.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Coccidioides antibody test

Frequently asked questions

Why is this test important?
This test helps diagnose or rule out *Coccidioides* infection, which can cause serious lung disease or spread to other organs. Early detection is key for managing symptoms and preventing complications, especially in high-risk individuals.
What does a positive result mean?
A positive result indicates the body has detected *Coccidioides* antibodies, meaning you may have been exposed or infected. However, symptoms may not appear until weeks or months later, and a single positive test does not always mean active disease. Your doctor will assess symptoms and other factors to guide next steps.
Can this test be used to monitor treatment?
No, this test is primarily for diagnosis or screening. If you have an active infection, your doctor may recommend additional tests (e.g., imaging or cultures) to monitor treatment progress.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy