Coccidioides Immunoglobulin G Antibody (Serum) – Immunoassay
This test measures the level of antibodies in your blood that your immune system produces in response to *Coccidioides*, a fungal infection commonly found in certain desert regions of the southwestern United States and parts of Latin America.
["This test helps doctors assess exposure to the fungus and whether your body is mounting an immune response."]
Key facts at a glance
- LOINC
- 103634-2
- Short code
- Coccidioides IgG+IgM Ser+CSF Ql IA-aCnc
- Synonyms
- Coccidioides IgG+IgM Ser+CSF Ql IA-aCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ia
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your healthcare provider may order this test if you live in or have traveled to an area with a high risk of *Coccidioides* exposure, or if you have symptoms like fever, cough, chest pain, or fatigue that could be linked to a fungal infection. It can also be used to monitor treatment progress or check for recurrence.
What to Expect Before the Test
No special preparation is needed. You’ll have a small needle inserted into your arm to draw blood. The process takes just a few minutes. If you’re pregnant, have a bleeding disorder, or take blood-thinning medications, let your provider know before the test.
What the Results Mean
Positive results indicate your immune system has detected *Coccidioides* antibodies, suggesting past or current infection. Higher levels may mean a stronger or more recent immune response. Negative results mean no detectable antibodies, but this doesn’t always rule out exposure.
Common Symptoms of Coccidioidomycosis
Symptoms may range from mild (flu-like) to severe (lung damage, skin rashes, or systemic illness). Some people have no symptoms at all. Common signs include fatigue, chest pain, persistent cough, or joint pain. If you experience these, discuss them with your provider.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
IgG Antibody to Coccidioides (Serum)
Frequently asked questions
This test is critical for diagnosing *Coccidioides* infection, guiding treatment decisions, and monitoring disease progression. It helps distinguish between active infection and past exposure, especially in high-risk populations.
Can I get this test if I’ve never lived in a high-risk area? Yes, if you’ve traveled to a region with *Coccidioides* exposure or have symptoms that could be linked to the infection, your provider may recommend this test.
Does this test detect active vs. past infection? This test detects antibodies, which indicate past or current exposure. However, it doesn’t always distinguish between active infection and immunity. Your provider may order additional tests for a clearer diagnosis.
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy