Serum IgG antibody to *Coccidioides* (immunoassay)
This test measures the level of antibodies in your blood that your immune system produces in response to *Coccidioides* infection, a fungal disease found in certain regions of the U.S. and other countries.
["Helps diagnose or monitor *Coccidioides* infection, often linked to Valley Fever."]
Key facts at a glance
- LOINC
- 46182-2
- Short code
- Coccidioides IgG Ser Ql
- Synonyms
- Coccidioides IgG Ser Ql
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
The test detects IgG antibodies specific to *Coccidioides*, a fungus that can cause illness ranging from mild flu-like symptoms to severe infections in some people. IgG antibodies typically develop after the initial infection and can persist long-term. This test is used to confirm exposure or active infection, especially in areas where the fungus is common.
Why Might You Need This Test?
Your healthcare provider may order this test if you live in or have traveled to regions with high *Coccidioides* risk (e.g., parts of the Southwest U.S.), have symptoms like fever, cough, or fatigue, or if you have a weakened immune system. It’s also used to track treatment progress or assess long-term exposure.
What to Expect Before the Test
No special preparation is needed. You’ll provide a blood sample, usually drawn from a vein in your arm. The test is quick and typically done in a lab setting. If you’re pregnant, have a bleeding disorder, or take blood thinners, let your provider know before the test.
What to Expect After the Test
You may experience mild bruising, soreness, or swelling at the injection site. Apply ice or a cold compress if needed. Avoid strenuous activity for a few hours afterward. Results are usually ready within a few days to a week, depending on lab processes.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Coccidioides IgG Antibody (Serum)
Frequently asked questions
Positive results indicate exposure to *Coccidioides*, suggesting past or current infection. Elevated levels may signal active disease, especially if symptoms like chest pain, persistent cough, or skin rashes are present. Low or negative results rule out recent exposure but don’t guarantee immunity. Follow-up testing or imaging may be needed for further evaluation.
Results are typically available within 5 to 7 business days, though some labs may process them sooner or later depending on volume. Your healthcare provider will discuss the findings with you during your follow-up visit.
Yes, this test is generally safe during pregnancy. However, it’s important to discuss your medical history and any potential risks with your healthcare provider before the test, as they may recommend additional monitoring or precautions.
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy