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Serum Antibody Screening for *Coccidioides* (IgG)

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies in your blood that may indicate exposure to *Coccidioides*, a fungus found in certain desert regions. Antibodies can develop after infection but do not always mean you have an active illness.

Quick summary

["This screening helps identify possible exposure to a fungal infection that can affect the lungs or other parts of the body."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
46183-0
Short code
Coccidioides IgM Ser Ql
Synonyms
Coccidioides IgM Ser Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test measures the presence of IgG antibodies against *Coccidioides*, a fungus that can cause infections. IgG antibodies are part of your immune system’s long-term response to infection. This test is used primarily to screen for past exposure rather than active disease.

Why Might You Need This Test?

Your healthcare provider may order this test if you live in or have traveled to an area with high risk of *Coccidioides* exposure (e.g., parts of the southwestern U.S., Central/South America). It may also be used if you have symptoms like cough, fever, or fatigue that could relate to a fungal infection.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm to draw blood. The process takes a few minutes, and you may feel a brief pinch. If you’re pregnant, have a bleeding disorder, or take blood-thinning medications, let your provider know.

What to Expect After the Test

You can return to your normal activities immediately. There’s no downtime, but watch for signs of bruising, swelling, or unusual bleeding at the injection site. If you experience severe pain or bleeding, contact your provider right away.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Coccidioides IgG Antibody Screen

Frequently asked questions

What Does a Positive or Negative Result Mean?
A positive result indicates your immune system has likely encountered *Coccidioides* antibodies, but it doesn’t confirm an active infection. You may need additional testing or follow-up to assess your health. A negative result means no detectable antibodies were found in this sample, but you could still be at risk if exposed recently.
How Often Should I Get This Test?
The frequency depends on your risk factors. If you live in a high-risk area or have symptoms, your provider may recommend retesting. If you’re asymptomatic and low-risk, this test may not be repeated unless advised otherwise.
Can This Test Be Done at Home?
No, this test requires a blood sample drawn in a clinical setting. Home-based tests for fungal infections are not standard for this specific screening.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy