Serum IgG Antibody to Coccidioides (IgG Antibody to Coccidioides Immunoassay)

Why This Test Is Done

Your healthcare provider may order this test if you live in or have traveled to areas with high risk for coccidioidomycosis, such as parts of the southwestern United States, Mexico, Central/South America, or Australia. They may also recommend it if you have symptoms like fever, cough, chest pain, or fatigue, or if you’ve had recent exposure to dust or soil in endemic regions.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, typically drawn from a vein in your arm. The test is usually done in a lab setting and results are available within a few days.

What the Results Mean

Positive results indicate the presence of IgG antibodies, suggesting past exposure to *Coccidioides*. However, antibodies may remain in your system for years even after infection has resolved. A positive result alone does not confirm active disease; further evaluation may be needed to assess symptoms or risk.

Possible Causes of Positive Results

A positive IgG antibody result can occur from past infection, vaccination (if applicable), or exposure to the fungus. False positives are rare but possible if you have other immune conditions or recent infections.