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C-reactive protein (mass concentration) in serum/plasma

Published: August 9, 2026Updated: August 17, 2026

This test measures the level of C-reactive protein, a protein produced by the liver in response to inflammation in your body.

Quick summary

["CRP helps identify and monitor inflammation, often used to check for infections or other inflammatory conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
99369-1
Short code
Cocksfoot IgG-mCnc
Synonyms
Cocksfoot IgG-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
22
Ref high
198
Critical range
— – 10000 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82553
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order a CRP test to evaluate signs of inflammation, detect infections (such as pneumonia or urinary tract infections), or monitor conditions like rheumatoid arthritis, heart disease, or autoimmune disorders. It can also help assess how well your body is responding to treatment for these conditions.

What to Expect Before the Test

No special preparation is usually needed. You may have a small needle inserted into your arm to draw blood. If you’re on blood thinners, let your provider know before the test.

What the Results Mean

CRP levels can vary based on health status, age, and other factors. Higher levels often indicate inflammation or infection, while lower levels suggest minimal or no inflammation. Your results will be discussed with you by your healthcare provider.

Common Conditions Monitored

CRP is commonly used to monitor conditions like infections, inflammatory diseases (such as lupus or arthritis), and to check for early signs of heart disease or other chronic inflammatory conditions.

Reference range

Adult males: 22-198 U/L; Females: 22-198 U/LN/A

Specimen: serum

No special preparation required. Inform provider of any chest pain or symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: CRP plays a critical role in diagnosing and managing inflammatory and infectious diseases. Elevated CRP levels can signal an active inflammatory process, guiding treatment decisions and follow-up care. It’s often used as a screening tool or to assess disease activity in conditions where inflammation is a key factor.

Short name

CRP (Serum/Plasma)

Frequently asked questions

What causes CRP levels to be high?
CRP levels can rise due to infections (like colds, flu, or urinary tract infections), injuries, surgeries, or certain medical conditions such as autoimmune diseases (like rheumatoid arthritis) or heart disease. Stress, smoking, and certain medications may also influence CRP levels.
How long does it take to get CRP test results?
Results from a CRP test are typically available within 1 to 3 business days, depending on your lab’s processing time. Your healthcare provider will discuss the findings with you during your follow-up visit.
Can CRP levels be affected by diet or lifestyle?
Yes, diet, exercise, smoking, and overall health can influence CRP levels. A healthy diet, regular physical activity, and avoiding smoking may help lower CRP levels and support better overall health.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy