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Creatinine Clearance (Calculated from Serum Creatinine and Estimated Glomerular Filtration Rate)

Published: August 9, 2026Updated: August 16, 2026

This test measures how well your kidneys filter waste products from your blood, helping assess kidney function over time.

Quick summary

["A calculated measure of kidney function based on blood and urine tests."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
107979-7
Short code
Coconut milk IgG Qn IA
Synonyms
Coconut milk IgG Qn IA
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Creatinine clearance is used to evaluate how effectively your kidneys are removing waste products from your blood. It helps doctors monitor kidney health, especially in people with diabetes, high blood pressure, or other conditions that may affect kidney function.

How the Test Works

Your healthcare provider will calculate creatinine clearance using a formula that combines your serum creatinine levels (a blood test) and an estimate of your glomerular filtration rate (GFR), which reflects kidney function. This test does not require a urine sample to be collected at home; results are derived from bloodwork alone.

What to Expect Before the Test

No special preparation is needed for this test. You may have a simple blood draw, often done while you sit comfortably. If you are being monitored for kidney function over time, your doctor may recommend periodic blood tests to track changes in your results.

What the Results Mean

Creatinine clearance results are typically reported as a rate (e.g., milliliters per minute or milliliters per hour). Lower values may indicate reduced kidney function, while higher values suggest better filtration. Your doctor will interpret these results in the context of your overall health and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Creatinine Clearance

Frequently asked questions

What could cause my creatinine clearance to change?
Several factors can influence creatinine clearance, including dehydration, muscle mass changes, certain medications, or underlying kidney diseases. If your results are abnormal, your doctor may recommend further testing or adjustments to your treatment plan to protect your kidney health.
How often should I get this test?
The frequency of creatinine clearance testing depends on your health condition. People with kidney disease, diabetes, or high blood pressure may need this test more often, while others with stable health may only need it periodically. Always follow your doctor’s recommendations.
Can diet or exercise affect my creatinine clearance?
Yes, diet and exercise can influence kidney function indirectly. Eating a balanced diet rich in fluids and reducing salt may help maintain healthy kidney function, while staying hydrated and exercising regularly can support overall cardiovascular health, which benefits kidney performance.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy