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C-reactive protein (serum/plasma concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures a protein produced by your liver in response to inflammation or infection. It helps doctors monitor conditions like arthritis, heart disease, or infections.

Quick summary

["CRP helps track inflammation, guiding treatment decisions and early detection of health issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
107840-1
Short code
Codfish IgG Qn IA
Synonyms
Codfish IgG Qn IA
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to check for signs of inflammation, infections, or other health problems. High levels can indicate conditions like arthritis, heart disease, or infections, while low levels may suggest no active inflammation.

What Does a High or Low Result Mean?

Results can vary based on your health and medical history. High CRP levels often signal inflammation, while low levels may mean your body isn’t responding to an infection or injury. Your doctor will interpret results in the context of your overall health.

Common Conditions Monitored

This test is commonly used to monitor conditions like rheumatoid arthritis, heart disease, infections (such as pneumonia or sepsis), and other inflammatory diseases. It can also help assess how well treatments are working.

Sample Collection and Preparation

A blood sample is taken from a vein, usually in your arm. The blood is then processed to separate the serum or plasma, which is sent to the lab for testing. You may be asked to fast before the test, but this isn’t always required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: CRP plays a key role in identifying and managing inflammatory conditions. It’s often used alongside other tests to provide a clearer picture of your health status, especially in chronic diseases like arthritis or cardiovascular issues. CRP can also help doctors decide when to start or adjust treatments for infections or autoimmune disorders.

Short name

CRP (High Sensitivity)

Frequently asked questions

What does a high CRP level mean?
A high CRP level suggests inflammation or infection in your body. This could be due to conditions like arthritis, heart disease, or infections such as pneumonia. Your doctor will review your results along with other factors to determine the cause and next steps.
How often should I get this test?
The frequency depends on your medical condition and treatment plan. Your doctor will let you know how often you need this test, whether it’s part of routine check-ups or monitoring for a specific health issue.
Can diet or exercise affect CRP levels?
Yes, lifestyle factors like diet, exercise, and smoking can influence CRP levels. Eating a healthy diet, staying active, and avoiding smoking may help lower inflammation and keep CRP levels more stable.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy