C-reactive protein (CRP) concentration

Why This Test Might Be Ordered

Your healthcare provider may order a CRP test to check for signs of inflammation, monitor chronic conditions (such as rheumatoid arthritis or heart disease), evaluate infections, or assess how well a treatment is working. It can also be used in screening for certain conditions like cardiovascular risk or autoimmune diseases.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours if your blood is drawn early in the morning. Avoid strenuous activity or excessive exercise 24 hours before the test. Let your provider know about any medications you’re taking, as some may affect results.

How the Test Is Performed

A blood sample is taken from a vein in your arm using a small needle. You may feel a brief pinch, but the procedure is quick and usually painless. The sample is then sent to a lab for analysis using an immunoassay method to measure CRP levels.

What the Results Mean

CRP levels vary depending on your health status. Higher-than-normal levels often indicate inflammation, infection, or an active disease process. Your provider will interpret results in the context of your medical history and other tests.