Donor Region-Wide Poor Sequence Quality Assessment (Genetic Testing)
This test evaluates the quality of genetic sequencing data collected from multiple donors across a specific region of their DNA. It helps identify areas where sequencing may be less reliable, which can be important for accurate genetic analysis.
["Assessing sequencing quality ensures reliable genetic test results for conditions like hereditary diseases or carrier screening."]
Key facts at a glance
- LOINC
- 92732-7
- Short code
- Codon or region w poor seq quality
- Synonyms
- Codon or region w poor seq quality
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- sequencing
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test checks for inconsistencies or errors in the genetic sequencing process. It looks at how well the DNA sequences align across different donors, identifying regions where sequencing might be poor quality. This helps ensure the results are accurate for further genetic analysis or diagnosis.
Why It Matters in Genetic Testing
Poor sequencing quality can lead to incorrect genetic interpretations, potentially affecting diagnoses or treatment plans. By identifying these issues early, healthcare providers can improve the reliability of genetic test results.
Common Causes of Poor Quality
Several factors can contribute to poor sequencing quality, such as technical issues during sample preparation, variability in donor DNA, or limitations in sequencing technology. This test helps pinpoint these problems to refine future testing methods.
How the Test Works
The test uses advanced algorithms to compare sequencing data from multiple donors. It flags regions where the consistency of sequences is lower, indicating potential areas of concern. This data is then reviewed by genetic experts to assess reliability.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
High-quality sequencing is critical for accurate genetic testing, especially in hereditary conditions or carrier screening. Poor quality can lead to false positives or negatives, which may impact treatment decisions or family planning. This test helps ensure that genetic results are trustworthy and actionable.
Frequently asked questions
What does a 'poor sequence quality' mean in this test?
How often is this test performed?
Can poor sequence quality affect my health or diagnosis?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy