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Serum or Plasma Creatinine Concentration (Qualitative or Quantitative Measurement)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood or plasma. It helps assess how well your kidneys are filtering blood.

Quick summary

["A creatinine test helps check kidney function by evaluating how well your kidneys remove waste from your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
71890-8
Short code
COHgb MFr.DF Bld
Synonyms
COHgb MFr.DF Bld
Category
hematology
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
12
Ref high
17.5
Critical range
7 N/A – 20 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85018
SNOMED
900000000000003004
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order a creatinine test to monitor kidney health, especially if you have symptoms like swelling, fatigue, or changes in urine output. It’s also used before certain procedures, during pregnancy, or when managing conditions like high blood pressure or diabetes.

What to Expect During the Test

A blood sample is taken from a vein in your arm. You may feel a small pinch, but it usually doesn’t cause discomfort. If you’re tested for plasma, your provider may use an anticoagulant to prevent clotting. The test itself is quick and painless.

Preparation and Timing

No special preparation is needed unless instructed by your provider. For some conditions, you might be asked to fast or avoid certain medications. Results are typically available within 24–48 hours, depending on your lab.

How Results Are Interpreted

Results are compared to a reference range specific to your lab, which accounts for factors like age, sex, and overall health. High levels may signal kidney problems, while very low levels could indicate muscle disorders or errors in measurement.

Reference range

Adult males: 13.5-17.5 g/dL; Females: 12.0-16.0 g/dLN/A

Specimen: whole-blood

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Creatinine levels are a key indicator of kidney function. Elevated levels suggest impaired filtration, which may require further testing or adjustments to medications. Low levels might prompt additional evaluation for conditions like malnutrition or liver disease.

Short name

Creatinine Level (Serum/Plasma)

Frequently asked questions

What causes creatinine levels to be high?
High creatinine levels can result from kidney disease, dehydration, severe muscle breakdown, or certain medications. If you notice unexplained fatigue, swelling, or changes in urine, discuss these symptoms with your provider.
What if my creatinine level is outside the normal range?
If your results are abnormal, your provider will likely order follow-up tests, such as a urine test or additional bloodwork, to investigate the cause. They may also adjust medications or treatments based on the findings.
Can diet affect creatinine levels?
Dietary changes—like high-protein meals—can temporarily influence creatinine levels, but they don’t alter the test’s primary purpose. Your provider will consider overall health and lifestyle when interpreting results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy