Colchicine Immunoassay (Plasma/Serum)

Why This Test Is Done

Your healthcare provider may order this test if you’re taking colchicine regularly to check if your dose is appropriate. It’s also used to detect colchicine poisoning or monitor levels in people with kidney issues, who may be at higher risk of side effects.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm or vein to draw blood. The process takes about 5 minutes, and you may feel a brief pinch. If you’re on colchicine, discuss your recent medication use with your provider before testing.

What the Results Mean

Results are compared to a reference range specific to colchicine, but exact values depend on your dose and health. High levels may indicate overdose or poor metabolism, while low levels could mean insufficient treatment. Your doctor will interpret results in the context of your medical history.

Common Causes of Abnormal Results

Overdose from excessive colchicine intake, kidney problems (which slow drug clearance), or interactions with other medications (e.g., certain antibiotics or antifungals) can raise levels. Liver disease, reduced kidney function, or rapid metabolism may lower levels.