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Colchicine Immunoassay (Plasma/Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of colchicine, a medication used to treat certain types of gout and inflammatory conditions, in your blood. It helps monitor your drug levels to ensure they remain safe and effective.

Quick summary

["Check your colchicine levels to avoid overdose or insufficient treatment."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
73429-3
Short code
Colchicine ind plt IgM SerPl Ql FC
Synonyms
Colchicine ind plt IgM SerPl Ql FC
Category
hematology
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you’re taking colchicine to manage conditions like gout, familial Mediterranean fever, or periodic fever syndromes. It’s also used to check for toxicity if you’ve had high doses or experienced side effects like nausea, vomiting, or muscle weakness.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm or a blood sample drawn from a vein. If you’re on colchicine, your doctor may advise stopping it temporarily or adjusting your dose before testing.

What the Results Mean

Results are compared to a general reference range for colchicine in blood. Very high levels may indicate overdose, while very low levels might suggest the medication isn’t working as intended. Your doctor will interpret results in the context of your symptoms and treatment plan.

Common Side Effects and Risks

Colchicine can cause side effects like stomach pain, dizziness, or fatigue. Rarely, it may lead to serious issues like kidney problems or low blood cell counts. If you experience severe symptoms (e.g., chest pain, irregular heartbeat, or confusion), seek medical attention immediately.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Colchicine levels are critical for managing therapeutic dosing. Toxicity can occur at higher concentrations, leading to organ damage or life-threatening complications. Regular monitoring helps prevent these risks and ensures the medication remains effective for your condition.

Short name

Colchicine Level

Frequently asked questions

What triggers a colchicine test?
A colchicine test may be ordered if you’re newly prescribed the medication, if your symptoms don’t improve, or if you experience side effects. Your doctor might also check levels if you’ve had a dose change or if you’re taking other medications that could interact with colchicine.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your doctor will contact you once they have the results, especially if they’re outside of the expected range.
Can I drink alcohol before the test?
Alcohol may not affect this test directly, but it can increase the risk of side effects like nausea or dizziness from colchicine. Avoid heavy alcohol use before testing if your doctor has advised it.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy