Colchicine Serum Mass Concentration
This test measures the amount of colchicine, a medication used to treat certain types of gout and inflammatory conditions, in your blood serum.
["Colchicine levels help monitor your treatment and check for potential toxicity."]
Key facts at a glance
- LOINC
- 12397-6
- Short code
- Colchicine SerPl-mCnc
- Synonyms
- Colchicine SerPl-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why Is This Test Done?
Your healthcare provider may order this test if you’re taking colchicine to manage conditions like gout, familial Mediterranean fever, or periodic fever syndromes. They may also check levels if you experience side effects like nausea, vomiting, or unusual weakness, which could indicate too much colchicine in your system.
What to Expect Before the Test
No special preparation is usually needed. You may be asked to fast for a few hours before the test, but always follow your provider’s instructions. Bring a list of all medications, including over-the-counter drugs and supplements, to share with your healthcare team.
What Happens During the Test?
A healthcare professional will draw blood from a vein in your arm using a small needle. You may feel a slight pinch, but the procedure is quick. The blood sample is then sent to a lab for analysis.
What Do the Results Mean?
Results are typically reported as a mass concentration of colchicine in your blood. High levels may signal toxicity, which can cause serious side effects. Your provider will interpret the results in the context of your symptoms, medical history, and medication use.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Elevated colchicine levels can indicate overdose or improper metabolism, leading to toxic effects such as heart rhythm disturbances, muscle weakness, or severe gastrointestinal issues. Regular monitoring is essential for patients on long-term colchicine therapy to prevent these risks.
Short name
Colchicine Level
Frequently asked questions
How often should I expect this test?
What are the normal reference ranges?
Can I eat or drink before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy