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Colchicine Serum Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of colchicine, a medication used to treat certain types of gout and inflammatory conditions, in your blood serum.

Quick summary

["Colchicine levels help monitor your treatment and check for potential toxicity."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
12397-6
Short code
Colchicine SerPl-mCnc
Synonyms
Colchicine SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you’re taking colchicine to manage conditions like gout, familial Mediterranean fever, or periodic fever syndromes. They may also check levels if you experience side effects like nausea, vomiting, or unusual weakness, which could indicate too much colchicine in your system.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for a few hours before the test, but always follow your provider’s instructions. Bring a list of all medications, including over-the-counter drugs and supplements, to share with your healthcare team.

What Happens During the Test?

A healthcare professional will draw blood from a vein in your arm using a small needle. You may feel a slight pinch, but the procedure is quick. The blood sample is then sent to a lab for analysis.

What Do the Results Mean?

Results are typically reported as a mass concentration of colchicine in your blood. High levels may signal toxicity, which can cause serious side effects. Your provider will interpret the results in the context of your symptoms, medical history, and medication use.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated colchicine levels can indicate overdose or improper metabolism, leading to toxic effects such as heart rhythm disturbances, muscle weakness, or severe gastrointestinal issues. Regular monitoring is essential for patients on long-term colchicine therapy to prevent these risks.

Short name

Colchicine Level

Frequently asked questions

How often should I expect this test?
Your provider will determine the frequency based on your treatment plan. Typically, tests may be done weekly or monthly, especially if you’re taking colchicine for a chronic condition or experiencing symptoms.
What are the normal reference ranges?
Reference ranges vary by lab and may not be widely published. Your results will be compared to your specific lab’s standards and discussed with your healthcare provider.
Can I eat or drink before this test?
Follow your provider’s instructions, but generally, fasting for 8–12 hours before the test is common for some blood tests, including colchicine levels. Avoid caffeine or alcohol before the test if advised.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy