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Colistin Resistance by Minimum Concentration (MIC) Testing (Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the lowest concentration of colistin needed to inhibit bacterial growth, helping determine if bacteria are resistant to this antibiotic.

Quick summary

["Assists healthcare providers in guiding antibiotic treatment for infections caused by colistin-resistant bacteria."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
98066-4
Short code
Colistin res mcr-(3-5) Islt/Spm Ql
Synonyms
Colistin res mcr-(3-5) Islt/Spm Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters for You

Colistin is an antibiotic used to treat serious infections caused by certain bacteria, including those resistant to other drugs. This test helps doctors decide whether your bacteria are sensitive or resistant to colistin, which is critical for choosing the best treatment plan.

What to Expect Before the Test

No special preparation is needed. A blood sample will be collected from a vein in your arm by a healthcare professional. The blood is then processed to determine the colistin resistance level.

What the Test Results Mean

Results indicate the minimum concentration of colistin required to stop bacterial growth. If your bacteria are resistant, this means higher doses of colistin may not be effective, and alternative treatments may be needed. Your doctor will discuss the results with you.

Common Reasons for This Test

This test is often performed on patients with infections suspected to involve colistin-resistant bacteria, such as those with urinary tract infections, pneumonia, or bloodstream infections caused by Gram-negative bacteria.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Colistin resistance is a growing concern in healthcare settings. Identifying resistance early helps prevent the spread of antibiotic-resistant bacteria and ensures appropriate treatment. It also supports infection control measures to limit further spread in hospitals and communities.

Short name

Colistin MIC Screening

Frequently asked questions

Will this test affect my antibiotic treatment plan?
Yes, the results will guide your doctor in deciding whether colistin or another antibiotic is the best choice for your infection. They will adjust your treatment plan based on the test findings.
How long will it take to get my test results?
Test results are typically available within 24 to 48 hours, depending on the laboratory’s processing time. Your doctor will contact you once they are ready.
Can I eat or drink before this test?
No special diet or fasting is required for this test. However, always follow your healthcare provider’s instructions regarding any medications or supplements you may be taking.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy