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Colonoscopy

Published: August 9, 2026Updated: August 16, 2026

A colonoscopy uses a flexible camera to examine the lining of the colon and rectum for polyps, inflammation, bleeding, or cancer.

Quick summary

["A colonoscopy can detect and help remove precancerous growths before they become cancer."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
67221-2
Short code
Colonoscopy PhenX
Synonyms
Colonoscopy PhenX
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
phenx
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

A colonoscopy is an examination of the large intestine using a thin, flexible tube with a camera. The scope is passed through the anus while your doctor looks for polyps, irritated tissue, bleeding, or other abnormalities. Small tissue samples may also be collected for laboratory examination.

Why might I need this test?

Colonoscopy may be recommended to screen for colorectal cancer, investigate blood in the stool, rectal bleeding, persistent abdominal symptoms, or unexplained changes in bowel habits. It may also be used to monitor certain people with previous polyps or inherited conditions that increase the risk of colorectal cancer.

How is the test performed?

Before the procedure, the bowel is cleaned with a prescribed bowel-preparation regimen. During the colonoscopy, the scope is gently moved through the colon so the entire lining can be examined. Polyps or suspicious areas may be removed, and tissue samples may be sent to a laboratory for further review.

How do I prepare for the test?

Follow the bowel-cleansing instructions exactly, because a poorly prepared colon can make the examination incomplete. Your care team will also provide instructions about food, fluids, and medicines. Tell the healthcare professional performing the procedure about kidney disease, swallowing problems, diabetes, blood thinners, or allergies before taking the preparation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Findings may include polyps, inflammation, ulcers, bleeding, narrowing, or other changes in the bowel lining. Polyps are important because some types can develop into colorectal cancer, although many are benign and can be removed during the procedure. Biopsy results may be needed to distinguish normal tissue from inflammation, precancerous changes, or cancer.

Short name

Colonoscopy

Frequently asked questions

Does a colonoscopy hurt?
Most people feel pressure or mild cramping during the procedure but do not experience significant pain. Medicine is usually given to help you relax, and the healthcare team can provide additional comfort measures.
Will I be able to go home afterward?
Usually, yes. You may need someone to drive you home if you received sedating medicine, and you should follow the team's instructions about eating, drinking, and resuming normal activities.
What happens if a polyp is found?
Small polyps may be removed during the colonoscopy, and samples of larger or suspicious growths may be sent for laboratory analysis. Your healthcare professional will explain the findings and recommend any follow-up needed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy