Colonoscopy with Endoscopic Evaluation and Biopsy (Colonoscopic Study)
This test involves examining your colon using a flexible tube with a camera (colonoscope) and may include taking small tissue samples for further testing. It helps detect abnormalities like polyps, inflammation, or signs of disease.
["A colonoscopy can reveal early signs of digestive issues and prevent serious health problems by removing harmful polyps early."]
Key facts at a glance
- LOINC
- 28023-0
- Short code
- Colonoscopy Study
- Synonyms
- Colonoscopy Study
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- colonoscopy
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What to Expect Before the Procedure
You’ll likely need to prepare by following a special diet and possibly taking laxatives to clear your bowels. Your doctor may also prescribe a clear liquid diet for a few days before the procedure. Avoid smoking and alcohol for 24 hours before the test. You may receive sedation to help you relax during the procedure.
During the Procedure
The procedure is done in a hospital or clinic setting. A nurse or technician will insert the colonoscope through your rectum and guide it through your colon. If needed, small tissue samples (biopsies) will be taken. The procedure usually takes 30 minutes to an hour. You may feel some discomfort, but the sedation helps keep you comfortable.
After the Procedure
After the procedure, you’ll rest for a short time before going home. You may experience mild cramping, bloating, or a slight fever. Avoid strenuous activity for the day. Follow your doctor’s instructions for any prescribed pain relievers or medications. You’ll need someone to drive you home since you’ll be sedated.
What the Procedure Can Detect
A colonoscopy can identify issues such as inflamed or damaged colon tissue, polyps (which can become cancerous over time), signs of inflammatory bowel disease (like Crohn’s disease or ulcerative colitis), and other abnormalities that may require further medical attention.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Colonoscopy with Biopsy
Frequently asked questions
Why is this test important?
How often should I get this test?
What are the risks or side effects?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy