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Amniotic fluid protein concentration (qualitative screening)

Published: August 9, 2026Updated: August 16, 2026

This test measures the general protein content in amniotic fluid, often used during pregnancy to assess fetal well-being or detect potential complications.

Quick summary

["A protein screening in amniotic fluid may help identify risks during pregnancy."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
38386-9
Short code
Color Amn
Synonyms
Color Amn
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

When is this test done?

Amniotic fluid protein screening is typically performed during prenatal care, particularly when monitoring high-risk pregnancies or evaluating fetal lung maturity. It may also be used in cases where there are concerns about fetal health or gestational complications.

What does the result mean?

The result is qualitative (yes/no) rather than a specific measurement. Abnormal findings may signal potential issues like preterm labor, fetal distress, or other pregnancy-related concerns, prompting further medical evaluation.

How is the test collected?

Amniotic fluid is collected through an amniocentesis procedure, where a small amount of fluid is extracted from around the fetus under sterile conditions. This is usually done by a healthcare provider in a hospital or clinic setting.

What preparation is needed?

No special preparation is required for this test. You may be asked to fast or avoid certain activities depending on the specific procedure, but this is determined by your healthcare provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Amniotic fluid protein screening

Frequently asked questions

Why would my doctor order this test?
Your doctor may order this test if you have a high-risk pregnancy, are at risk for preterm labor, or if there are concerns about fetal health. It helps monitor conditions like gestational diabetes, infections, or other complications.
What are the possible risks or side effects?
The most common risk is a minor discomfort or slight cramping during the procedure. Rarely, there may be complications such as infection or bleeding, but serious risks are uncommon with modern medical practices.
How soon will I get my results?
Results are typically available within a few days to a week after the procedure, depending on the lab and your healthcare provider’s workflow.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy