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Total IgE (Immunoglobulin E) Level

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin E (IgE) in your blood. IgE is a protein that your immune system produces in response to allergens, such as pollen, dust, or certain foods.

Quick summary

["IgE levels help identify allergies and allergic reactions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
61214-3
Short code
Common Ragweed IgE/IgE total %
Synonyms
Common Ragweed IgE/IgE total %
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does IgE Measure?

IgE is part of your immune system’s response to allergens. When your body encounters an allergen it doesn’t recognize as harmless, IgE helps trigger allergic reactions like sneezing, itching, or swelling. This test helps doctors determine if you have an allergic reaction or sensitivity to specific substances.

Why Might You Need This Test?

Your doctor may order this test if you have symptoms like hives, asthma, hay fever, or if you’ve been exposed to potential allergens. It can also help diagnose conditions like allergic rhinitis, eczema, or food allergies.

How Is the Test Performed?

A small blood sample is taken from your arm, usually by a healthcare professional. The blood is then sent to a lab for analysis. The test checks for the presence and amount of IgE in your serum or plasma.

What Are Common Results?

Results are typically reported as a numerical value (in IU/mL) that reflects your IgE level. Higher levels may suggest an allergic reaction or sensitivity to certain triggers.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated IgE levels often indicate an allergic reaction to specific substances, such as pollen, pet dander, or certain foods. Doctors use these results to guide allergy testing, treatment plans, and management strategies for conditions like asthma, eczema, or food allergies. However, IgE alone doesn’t always pinpoint the exact cause of an allergy, so further testing may be needed.

Short name

IgE Total

Frequently asked questions

What does a high IgE level mean?
A high IgE level suggests your immune system is reacting to certain allergens, which may cause symptoms like sneezing, itching, or skin rashes. Your doctor may recommend allergy testing or avoidance strategies to manage your condition.
Can IgE levels change over time?
Yes, IgE levels can fluctuate depending on exposure to allergens, overall health, and treatment. If you’re undergoing allergy treatment (like immunotherapy), your levels may change as your body adapts.
Is there anything I can do to lower my IgE levels naturally?
While IgE levels are influenced by your immune response, avoiding known allergens, managing stress, and maintaining a balanced diet may help reduce symptoms. Always consult your doctor before making changes, especially if you have a diagnosed allergy.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy