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Serum/Plasma Creatinine Concentration (Quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood or plasma. It helps assess how well your kidneys are filtering blood.

Quick summary

["A creatinine test helps check kidney function by measuring how well your kidneys remove waste from your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
107555-5
Short code
Comp C3+C4+ C1q Ab.IgG pnl SerPl
Synonyms
Comp C3+C4+ C1q Ab.IgG pnl SerPl
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Your kidneys filter waste products, including creatinine, from your blood. If your kidneys aren’t working well, creatinine levels can rise. This test helps doctors detect early kidney problems, monitor kidney disease progression, or evaluate kidney function before certain procedures.

What to Expect Before the Test

No special preparation is needed for this test. You may have a small needle inserted into a vein (usually in your arm) to draw blood. If you’re tested for plasma, your blood will be processed immediately. Avoid heavy exercise or high-protein meals 24 hours before testing if instructed by your provider.

What the Results Mean

Higher-than-normal levels may indicate reduced kidney function, while lower-than-normal levels could suggest dehydration or other conditions affecting muscle metabolism. Your doctor will interpret results in relation to your overall health and medical history.

Common Causes of Abnormal Results

Elevated creatinine levels may be due to kidney disease, dehydration, severe muscle injury, or conditions like diabetes or heart failure. Lower levels might be linked to overhydration or muscle wasting. Always discuss results with your healthcare provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Creatinine Level

Frequently asked questions

How often will I need this test?
Your doctor may order this test periodically to monitor kidney function, especially if you have conditions like diabetes, high blood pressure, or a history of kidney problems. Frequency depends on your health status and treatment plan.
Can diet affect my creatinine levels?
Yes, high-protein diets can temporarily increase creatinine levels. Avoid excessive protein intake 24 hours before testing if advised by your provider to get an accurate result.
What if my results are out of range?
If your results are abnormal, your doctor will review them with you and may recommend further tests or adjustments to your treatment plan. Follow-up may include additional kidney function tests or lifestyle recommendations.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy