Comprehensive Diagnostic Serum Protein Electrophoresis with Bromocresol Green Staining
This test measures the distribution of proteins in your blood serum using electrophoresis and a dye (bromocresol green) to help identify abnormal protein patterns, which may indicate conditions like inflammation, infections, or inherited disorders.
["This test helps diagnose and monitor conditions affecting protein balance in your blood."]
Key facts at a glance
- LOINC
- 111927-0
- Short code
- Comprehensive diagnosis SB Endscpy
- Synonyms
- Comprehensive diagnosis SB Endscpy
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- endoscopy
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
Electrophoresis separates blood proteins based on their size and electrical charge, creating distinct bands. Bromocresol green dye binds to certain proteins, allowing for visual differentiation. This process helps identify abnormal protein levels or patterns, such as those seen in conditions like multiple myeloma, liver disease, or chronic inflammation.
Why It’s Ordered
Your healthcare provider may recommend this test if you have symptoms like unexplained weight loss, fatigue, swollen glands, or signs of organ dysfunction. It’s also used to monitor conditions like autoimmune diseases, infections, or inherited metabolic disorders.
How the Test Works
A blood sample is drawn and placed in an electric field, causing proteins to migrate toward the opposite charge. The dye highlights specific protein fractions, creating a profile that reflects their relative amounts.
Sample Preparation
The test uses serum (liquid part of blood after clotting) collected from a vein. No special preparation is needed, but fasting may be advised depending on your provider’s instructions.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Frequently asked questions
How might abnormal results affect my health?
What does it mean if my results are normal?
How often should I get this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy