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Congenital Lactic Acid, Multi-Specimen (Amniotic Fluid, Blood, and Dried Blood Spot), Laboratory-Developed Test

Published: August 9, 2026Updated: August 16, 2026

This test measures lactic acid in multiple specimen types to help evaluate for congenital (inherited) causes of lactic acidosis, a condition in which lactate builds up abnormally in the body.

Quick summary

["Testing lactate across several specimen types helps distinguish inherited metabolic causes of lactic acidosis from other explanations."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
105352-9
Short code
Congen lactic acid multi anl Bld/T
Synonyms
Congen lactic acid multi anl Bld/T
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What This Test Measures

Lactic acid (lactate) is a normal byproduct of energy production in your cells. This laboratory-developed test measures lactate levels across more than one specimen type—such as amniotic fluid, blood, and dried blood spots—to give a fuller picture of how the body is handling lactate.

Why Multiple Specimens Are Used

Different specimen types can provide complementary information. Blood lactate reflects the current balance of lactate production and clearance, while other specimens may support evaluation in specific clinical settings such as newborn or prenatal assessment. Using several specimens helps the care team interpret results in context.

What to Expect

Depending on the situation, a blood sample from a vein or heel/finger stick (dried blood spot), and in some cases an amniotic fluid sample, may be collected. Collection is typically quick, though heel or finger sticks may cause brief discomfort.

How Results Are Used

Results are interpreted together with your symptoms, medical history, and other tests. Lactate levels can be affected by many factors, so an abnormal value alone does not confirm a diagnosis; clinicians use the pattern across specimens and the overall clinical picture.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Lactic acidosis can result from inherited metabolic disorders, low oxygen states, certain medications, and other conditions. Measuring lactate across multiple specimen types can help clinicians evaluate for congenital metabolic causes, but results must be interpreted in the full clinical context and are not diagnostic on their own.

Short name

Congenital Lactic Acidosis Panel

Frequently asked questions

Does an elevated lactate always mean I have an inherited disorder?
No. Lactate can rise for many reasons, including temporary oxygen deprivation, intense exercise, certain medications, and other illnesses. An elevated result is a clue that requires interpretation alongside other findings.
Is this test painful?
Blood collection may cause brief discomfort, especially heel or finger sticks used for dried blood spots. Amniotic fluid collection, when performed, is a specialized procedure that your care team will explain in advance.
Can I eat or drink before this test?
Preparation depends on which specimens are being collected and your care team's instructions. Follow the specific fasting or preparation guidance provided by your clinician or laboratory.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy