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Connective Tissue Glycoprotein Serum Level (Electrophoresis)

Published: August 9, 2026Updated: August 16, 2026

This test measures levels of specific proteins in your blood that are part of the connective tissue network, which supports and connects tissues throughout your body. These proteins play roles in maintaining tissue structure, healing, and immune function.

Quick summary

["Understanding your connective tissue protein levels can help identify potential health concerns related to tissue integrity or function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
95267-1
Short code
Connective Tiss IgG Pnl SerPl
Synonyms
Connective Tiss IgG Pnl SerPl
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms or conditions linked to abnormal connective tissue proteins, such as chronic inflammation, autoimmune disorders, or suspected genetic connective tissue disorders. It could also be part of a broader evaluation for unexplained symptoms like joint pain, skin changes, or organ dysfunction.

What to Expect Before the Test

No special preparation is typically needed. You may be asked to fast for 8–12 hours before the draw if your provider specifies it, but this is less common for this type of test. Bring your medical records or a list of current medications to your appointment.

What the Test Involves

A healthcare professional will draw blood from a vein in your arm. The blood sample is then sent to a lab for analysis using electrophoresis, a method that separates proteins based on size and charge. This helps identify and quantify different connective tissue glycoproteins in your serum.

What the Results Mean

Results provide a profile of your blood’s connective tissue glycoprotein composition. Abnormal patterns may indicate underlying issues like excessive protein breakdown, abnormal protein synthesis, or conditions affecting connective tissue structure (e.g., certain genetic disorders or chronic diseases). Your provider will interpret these results in the context of your symptoms and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Serum Connective Tissue Glycoprotein Profile

Frequently asked questions

How might my test results affect my care?
Your results will be reviewed by your healthcare provider to determine if they align with known patterns of connective tissue disorders or systemic conditions. Elevated or altered levels of specific glycoproteins might suggest conditions like rheumatoid arthritis, certain skin disorders, or metabolic syndromes. Low or missing proteins could point to conditions affecting protein synthesis or degradation. Always discuss your results with your provider, as they will tailor recommendations based on your overall health and needs.
What are the most common reasons for abnormal results?
Abnormal results could stem from a variety of factors, including chronic inflammation, autoimmune diseases, genetic predispositions, or metabolic disorders. For example, certain connective tissue disorders may lead to specific glycoprotein imbalances, while infections or medications can temporarily alter protein levels. Your provider will explore these possibilities during your evaluation.
How often will I need this test?
The frequency of this test depends on your symptoms, medical history, and provider recommendations. Some patients may need follow-up testing if initial results suggest a potential condition, while others may only require it as part of a one-time evaluation. Regular monitoring may be advised if you have a known connective tissue disorder or related condition.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy