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Serum Free Copper Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of free copper (not bound to proteins) in your serum. Copper is an essential mineral that plays a role in many body functions, including energy production and immune support.

Quick summary

["Understanding your free copper levels can help identify potential deficiencies or excesses that may affect your health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
96257-1
Short code
Copper free SerPl-mCnc
Synonyms
Copper free SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
86430
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like fatigue, weakness, or neurological issues that could be linked to copper metabolism problems. It may also be checked in cases of suspected Wilson’s disease, liver disease, or other conditions affecting copper absorption or storage.

What to Expect Before the Test

No special preparation is usually needed. You’ll have a small needle inserted into your arm to draw blood. If you’re nervous, let your healthcare provider know—they can offer comfort measures.

What the Results Mean

Results are compared to general reference ranges for healthy adults. Abnormal levels may signal conditions like copper toxicity, deficiency, or metabolic disorders. Your provider will discuss findings in the context of your overall health.

Common Conditions Linked to Free Copper Levels

High free copper levels might be linked to liver disease or Wilson’s disease, while low levels could indicate malabsorption, certain genetic disorders, or nutritional deficiencies. Always review results with your doctor.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Free Copper Level

Frequently asked questions

How often should I get this test?
Your provider will determine the frequency based on your symptoms, medical history, and other test results. Routine screening for copper levels isn’t standard unless you have specific risk factors or conditions.
What causes free copper levels to change?
Changes can occur due to liver disease, genetic disorders (like Wilson’s disease), certain medications, or dietary factors. Lifestyle habits, such as alcohol use or smoking, may also influence copper metabolism.
Can I adjust my diet to affect free copper levels?
While diet can influence copper absorption, it’s not a reliable way to alter free copper levels. Focus on a balanced diet and consult your doctor before making significant dietary changes, especially if you have health conditions.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy