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Serum Copper Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of copper present in your blood serum, which helps assess copper metabolism and identify potential deficiencies or excesses.

Quick summary

["Your copper levels can affect how well your body absorbs iron and supports liver function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
109635-3
Short code
Copper Msmt RBC
Synonyms
Copper Msmt RBC
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
4.2
Ref high
5.9
Critical range
2 N/A – 7 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85041
SNOMED
900000000000003001
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like fatigue, weakness, or liver issues, or if you have conditions like Wilson’s disease (a copper storage disorder) or Wilson’s disease screening. It may also be checked in cases of chronic kidney disease, malabsorption disorders, or unexplained anemia.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the draw if your test involves a fasting sample. Bring any medications or supplements you’re taking to your appointment.

What the Results Mean

Results are interpreted by your healthcare provider based on your overall health, symptoms, and medical history. Abnormal levels may signal underlying conditions requiring further evaluation.

Common Conditions Linked to Copper Levels

Low copper levels might indicate poor nutrition, liver disease, or certain medications. High levels could suggest Wilson’s disease, kidney disease, or copper poisoning from supplements.

Reference range

Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A

Specimen: whole-blood

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Serum Copper

Frequently asked questions

What causes copper levels to be low?
Low copper levels can result from poor diet (low copper intake), liver disease, chronic kidney disease, or certain medications that interfere with copper absorption.
What causes copper levels to be high?
High copper levels are often linked to Wilson’s disease (a genetic disorder), kidney disease, or excessive copper intake from supplements or medications.
Does diet affect copper test results?
Yes, dietary factors like copper-rich foods (e.g., organ meats, shellfish) or supplements may influence results. Your provider may ask about recent dietary changes or supplements.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy