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Serum Copper (Plasma) Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of copper, a trace mineral, in your blood. Copper helps with iron absorption, red blood cell production, and immune function.

Quick summary

["Copper levels can help diagnose or monitor conditions affecting copper metabolism or related health risks."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
105459-2
Short code
Copper pnl SerPl
Synonyms
Copper pnl SerPl
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Copper is essential for many bodily functions, including energy production and maintaining healthy skin and nerves. Abnormal levels may indicate conditions like Wilson’s disease (a copper storage disorder), liver problems, or certain genetic disorders.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if your blood is drawn early in the morning. Wear comfortable clothing and bring your medical records if you have conditions like liver disease or kidney problems.

How the Test Is Done

A healthcare provider will draw blood from a vein in your arm using a small needle. The blood sample is sent to a lab for analysis. The test typically takes a few minutes, and you may feel slight discomfort but no lasting effects.

What the Results Mean

Results are compared to a general reference range for healthy adults. Low copper levels may suggest poor absorption, liver disease, or certain medications affecting copper metabolism. High levels could indicate liver issues, Wilson’s disease, or excessive copper intake.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Copper Level

Frequently asked questions

Could low copper levels affect my energy or immune system?
Yes, copper deficiency can lead to fatigue, weakness, or a weakened immune system. It may also increase the risk of anemia or nerve damage. If your test results are low, your doctor may recommend dietary changes, supplements, or further testing to identify the cause.
What if my copper level is higher than normal?
Elevated copper levels can signal underlying liver problems, Wilson’s disease, or other metabolic disorders. Your doctor may order additional tests, such as liver function tests, to investigate further. Treatment depends on the cause but may include medications or lifestyle adjustments.
Do certain medications or foods affect copper levels?
Yes, some medications (like antacids or certain antibiotics) or foods (like cashews, liver, or shellfish) can influence copper levels. If you’re taking medications or eating a specific diet, let your doctor know to avoid misleading results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy