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Serum Copper Concentration (Mass)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of copper present in your blood serum, which can help assess copper metabolism and identify potential deficiencies or excesses.

Quick summary

["Understanding your copper levels may help diagnose or monitor conditions related to copper absorption or storage."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
5630-9
Short code
Copper RBC-mCnc
Synonyms
Copper RBC-mCnc
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
4.2
Ref high
5.9
Critical range
2 N/A – 7 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85041
SNOMED
900000000000003001
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have symptoms like nausea, vomiting, or abdominal pain, or if you have conditions such as Wilson’s disease (a genetic disorder affecting copper metabolism), liver disease, or kidney problems. It may also be used to monitor treatment for certain disorders or to check for copper toxicity.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for a few hours before the blood draw if your test is part of a comprehensive metabolic panel. Wear comfortable clothing and plan to rest for a short time afterward.

What Happens During the Test?

A healthcare professional will draw blood from a vein in your arm. You may feel a slight pinch, but it typically doesn’t cause discomfort. The blood sample is then sent to a lab for analysis.

What Do the Results Mean?

Results are compared to standard reference ranges, but they can vary by lab. Low copper levels may suggest malabsorption, liver disease, or certain medications affecting copper uptake. High levels could indicate Wilson’s disease or other metabolic issues. Always discuss your results with your provider.

Reference range

Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A

Specimen: whole-blood

No special preparation required. Stay well hydrated.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Serum Copper

Frequently asked questions

What causes low copper levels?
Low copper levels can result from conditions like celiac disease, liver disease, or certain medications that interfere with copper absorption. Dietary deficiencies (rarely) or malabsorption syndromes may also play a role.
What are the symptoms of copper deficiency?
Symptoms may include fatigue, weakened immune function, hair loss, or bone pain. In severe cases, it can affect nerve function or lead to anemia. Symptoms are often subtle and may not appear until deficiency is advanced.
How is copper toxicity typically treated?
Treatment for copper toxicity depends on the cause. If due to Wilson’s disease, medications like penicillamine or triethylene tetramine are used to reduce copper absorption. In other cases, dietary adjustments or chelation therapy may be recommended. Always follow your provider’s guidance.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy