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Copper concentration in serum or plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of copper, a trace mineral essential for various bodily functions, found in your blood.

Quick summary

["Copper levels help assess liver function and potential copper toxicity or deficiency."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
5631-7
Short code
Copper SerPl-mCnc
Synonyms
Copper SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why is this test done?

Your healthcare provider may order this test to check for conditions affecting copper metabolism, such as liver disease, Wilson’s disease (a genetic disorder causing copper buildup), or copper deficiency. It may also be used to monitor treatment responses or detect signs of copper toxicity.

What does the result mean?

Results are not provided with specific numeric ranges since they vary by lab and health status. Your provider will interpret the result in relation to your overall health and symptoms. High levels might suggest liver issues or Wilson’s disease, while very low levels could indicate malabsorption or certain genetic conditions.

Common reasons for testing

Tests for serum copper are often performed when symptoms like fatigue, nausea, neurological issues, or liver problems are present. It may also be part of a broader evaluation for genetic disorders or metabolic conditions.

What to expect during the test

A small blood sample is drawn from a vein, usually in your arm. You may feel a slight pinch, but it typically takes only a few minutes. No special preparation is needed unless instructed otherwise.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance

Short name

Serum Copper

Frequently asked questions

What might abnormal results indicate?
Elevated copper levels may signal liver disease, Wilson’s disease, or other metabolic disorders. Low copper levels could suggest malabsorption, certain medications, or genetic factors affecting copper absorption.
How often should I get this test?
Your provider will determine the timing based on your symptoms, medical history, and treatment plan. Follow-up tests may be scheduled if initial results are outside expected ranges.
Can diet affect copper test results?
Dietary copper intake is minimal and unlikely to significantly impact this test. However, certain medications (e.g., antibiotics, antacids) or liver conditions may influence results. Avoid alcohol before testing if advised by your provider.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy