Skip to content

Copper in Serum or Plasma (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of copper, a trace mineral essential for many bodily functions, found in your blood.

Quick summary

["Your blood copper levels help assess liver function and potential copper-related health risks."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
20778-7
Short code
Copper Spec-mCnc
Synonyms
Copper Spec-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like fatigue, nausea, or abdominal pain, or if you have conditions such as Wilson’s disease (a genetic disorder affecting copper metabolism) or liver disease. It may also be part of routine monitoring for certain medications or genetic testing.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the draw if your lab uses fasting protocols. Wear a loose shirt for easy access to your vein.

What Happens During the Test

A healthcare professional will insert a small needle into a vein in your arm to collect blood. You may feel a slight pinch, but it’s over quickly. The blood sample is then sent to a lab for analysis.

What the Results Mean

Results are compared to general reference ranges for healthy adults, though individual needs may vary. Abnormally high or low levels may signal underlying health concerns that require further evaluation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

High copper levels in blood can indicate liver disease, Wilson’s disease, or copper overload syndromes. Low levels may suggest malabsorption, liver dysfunction, or certain genetic disorders. Always discuss results with your provider for personalized interpretation.

Short name

Serum/Copper

Frequently asked questions

How often should I get this test?
This test is typically ordered as needed for diagnosis, monitoring, or research. Your provider will determine the frequency based on your health status and medical history.
What causes copper levels to change?
Copper levels can be affected by liver disease, genetic conditions (like Wilson’s disease), certain medications, or dietary factors. Stress, infections, or pregnancy may also influence results.
Can I eat or drink before the test?
Follow your provider’s instructions, but generally, fasting is not required unless specified. Avoid caffeine or alcohol before the draw, as they may affect results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy