Skip to content

Serum Copper Concentration (Mass)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of copper in your blood serum, which helps assess copper metabolism and identify potential deficiencies or excesses.

Quick summary

["Copper levels can affect health, especially in conditions like Wilson’s disease or copper overload."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
99383-2
Short code
Copper Wat-sCnc
Synonyms
Copper Wat-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like fatigue, nausea, or skin changes, or if you have a history of conditions linked to copper imbalance, such as Wilson’s disease or liver issues. It may also be part of routine screening for certain genetic disorders or metabolic conditions.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for a few hours before the blood draw if your test involves a specific timing (e.g., 24-hour urine collection). Avoid consuming copper-rich foods or supplements for 24 hours prior if instructed.

What Happens During the Test

A healthcare professional will draw blood from a vein in your arm. The sample is then sent to a lab for analysis using a method that detects copper concentration in your serum.

What the Results Mean

Results are compared to reference ranges for healthy adults, but exact values can vary by lab. Low levels may suggest copper deficiency, while high levels could indicate overabsorption or underlying health conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal copper levels can signal underlying health issues. Low copper may lead to weakened immune function or neurological problems, while high copper can cause liver damage or other systemic effects. This test is critical for diagnosing conditions like Wilson’s disease, where copper buildup is dangerous.

Short name

Copper Level

Frequently asked questions

What causes copper levels to be low?
Copper deficiency can result from poor diet (low intake of copper-rich foods like shellfish, nuts, and organ meats), malabsorption issues (e.g., celiac disease), or certain medications that interfere with copper absorption.
What are common symptoms of copper deficiency?
Symptoms may include fatigue, weakness, hair loss, skin changes, or an increased risk of infections. In severe cases, neurological symptoms like numbness or balance problems may occur.
How is copper overload typically treated?
Treatment for copper overload depends on the cause. If due to Wilson’s disease, medications like penicillamine may be prescribed to help remove excess copper. Dietary restrictions or chelation therapy may also be recommended.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy