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Cortisol, Serum (10 AM)

Published: August 9, 2026Updated: August 16, 2026

This test measures your cortisol levels in the morning to help assess your body’s ability to produce cortisol, a hormone involved in managing stress, immune response, and metabolism.

Quick summary

["A morning cortisol test helps doctors check for adrenal gland issues or stress-related hormone imbalances."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
58633-9
Short code
Cortis 10 AM SerPl-mCnc
Synonyms
Cortis 10 AM SerPl-mCnc
Category
hormone
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you have symptoms like fatigue, weight changes, salt cravings, or unexplained low blood pressure. It can also be used to diagnose conditions such as Cushing’s syndrome or adrenal insufficiency.

What to Expect Before the Test

No special preparation is needed, but you should fast for 8–12 hours before the test if instructed. Bring your morning urine sample if testing for cortisol in urine is part of your evaluation.

How the Test Works

A blood sample is taken from a vein in your arm, usually in the morning. The sample is sent to a lab to measure cortisol concentration in your serum.

What the Results Mean

Results help determine if your cortisol levels are too high or too low, which can indicate hormonal imbalances or other health concerns. Your doctor will interpret the results in relation to your symptoms and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Morning Cortisol Level

Frequently asked questions

Will I need to fast before this test?
Yes, fasting for 8–12 hours before the blood draw is often required to get an accurate morning cortisol measurement. Follow your doctor’s specific instructions.
Can I take medications before the test?
Some medications may affect cortisol levels. Always inform your doctor or lab technician about all medications, supplements, or recent treatments you’re taking.
How long will I need to wait for my results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your doctor will discuss the findings with you during your follow-up.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy