Corticosteroid (Mass Concentration) in Serum/Plasma

Why This Test Might Be Ordered

Your doctor may recommend this test if you have symptoms like weight changes, fatigue, high blood pressure, or unexplained muscle weakness. It could also be used to diagnose or monitor conditions like Cushing’s syndrome, adrenal insufficiency, or to assess how your body responds to steroid treatments.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the blood draw if cortisol levels are being specifically measured for timing (e.g., morning vs. evening). Avoid caffeine or smoking for a few hours before testing.

What the Results Mean

Results may indicate whether your body produces too much or too little corticosteroid. High levels might suggest overactive adrenal glands or long-term steroid use, while low levels could point to adrenal gland problems or other hormonal imbalances.

Common Conditions Affecting Results

Factors like stress, illness, medications (e.g., birth control pills, some antidepressants), or recent infections can temporarily alter corticosteroid levels. Chronic conditions like diabetes or kidney disease may also influence results.