Cortisol, mass concentration in serum/plasma

Why Might You Need This Test?

Your doctor may order cortisol testing to diagnose or monitor conditions like adrenal gland disorders (such as Cushing’s syndrome or Addison’s disease), evaluate stress responses, or check for hormonal imbalances. It can also help assess how well medications affecting cortisol levels are working.

What to Expect During the Test

A blood sample is taken from a vein in your arm. You may feel a slight pinch, but it usually doesn’t cause discomfort. The sample is sent to a lab for analysis. No special preparation is typically needed, but your doctor may advise fasting or timing the test around certain times of the day (e.g., morning for baseline levels).

How the Results Are Used

Results help determine if your cortisol levels are too high, too low, or within the normal range. Abnormal levels may indicate underlying health issues that need medical attention, such as hormonal imbalances or conditions affecting your adrenal glands.

Common Conditions Linked to Cortisol Testing

Cortisol testing is often used to diagnose or manage conditions like Cushing’s syndrome (excess cortisol), Addison’s disease (low cortisol), or to evaluate responses to stress or medications that affect cortisol production.