Corynebacterium DNA Detection by Nucleic Acid Amplification Probe (Qualitative)
This test checks for the presence of genetic material from *Corynebacterium* bacteria, including *Corynebacterium diphtheriae* (the cause of diphtheria), using a specialized probe to detect DNA. It helps confirm infections in clinical samples.
["This test helps diagnose serious bacterial infections by detecting genetic material in your sample."]
Key facts at a glance
- LOINC
- 92786-3
- Short code
- Corynebacterium DNA Bld Pos Ql NAA+probe
- Synonyms
- Corynebacterium DNA Bld Pos Ql NAA+probe
- Category
- chemistry
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- probe-amp-tar
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test uses a molecular probe to identify specific DNA sequences linked to *Corynebacterium* bacteria, including *C. diphtheriae*. This is done through a process that amplifies and detects genetic material, ensuring high sensitivity for detecting low levels of infection.
How the Test Works
The test involves extracting DNA from your sample (such as blood, throat swab, or other clinical material) and applying a probe that binds to the target bacterial DNA. If the probe matches the DNA, it triggers a detectable signal, confirming the presence of the bacteria.
Why It’s Done
This test is primarily used to diagnose infections caused by *Corynebacterium* species, particularly *C. diphtheriae*, which can lead to serious illnesses like diphtheria. It is often requested when symptoms such as sore throat, fever, or respiratory issues are present and bacterial infection is suspected.
Sample Collection
The sample for this test is typically collected from a clinical site (e.g., throat swab, wound, or other affected area) or may be drawn from blood or other bodily fluids. Your healthcare provider will determine the best sample type based on your symptoms and medical history.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
C. diphtheriae/Naevi DNA Test (Qualitative)
Frequently asked questions
This test plays a critical role in confirming bacterial infections that may not respond to standard cultures or other diagnostic methods. Early detection of *Corynebacterium* infections, such as diphtheria, is essential for prompt treatment and preventing complications or spread of the infection.
What does a negative result mean? A negative result means no detectable *Corynebacterium* DNA was found in the sample. However, this does not rule out infection entirely, especially if symptoms persist. Follow-up testing or clinical evaluation may still be recommended.
Can I take anything before the test? Avoid using antibiotics or other medications that may affect bacterial growth in the sample for at least 24 hours before testing, as this may impact results. Follow your healthcare provider’s instructions.
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy