Cotinine concentration in urine

Why Is This Test Done?

Your healthcare provider may order this test to evaluate exposure to tobacco smoke, monitor nicotine dependence, or check for secondhand smoke exposure in children or non-smokers. It’s often used in studies or clinical settings to measure nicotine levels indirectly.

What Does the Result Mean?

Results are not provided with specific numeric ranges, as they vary by lab and context. Higher levels may indicate recent tobacco exposure, while lower levels suggest minimal or no exposure. Interpretation depends on clinical context and timing (e.g., 24-hour urine collection).

How Is the Test Performed?

You’ll provide a urine sample (typically collected over 24 hours) in a sterile container. The sample is sent to a lab where cotinine is measured using a sensitive analytical method, often immunoassay or chromatography.

What Are Common Causes of Abnormal Results?

Elevated cotinine levels may be due to recent tobacco smoking (including vaping or chewing tobacco) or secondhand smoke exposure. Very low or undetectable levels suggest minimal or no exposure. Other factors, like certain medications or metabolic differences, may also influence results.