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Total Cottonseed Ige (Immunoglobulin E) Antibody Level

Published: August 9, 2026Updated: August 17, 2026

This test measures the total amount of Immunoglobulin E (IgE), a type of antibody linked to allergic reactions and certain immune responses.

Quick summary

["IgE levels help identify allergies or immune system sensitivities."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
61340-6
Short code
Cottonseed IgE/IgE total %
Synonyms
Cottonseed IgE/IgE total %
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
17
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Immunoglobulin E (IgE)?

IgE is a protein produced by your immune system in response to allergens like pollen, dust, or certain foods. High levels may signal allergies, asthma, or other allergic conditions.

Why Might You Need This Test?

Your doctor may order this test if you have symptoms like sneezing, itching, hives, or breathing difficulties, or if you have a history of allergies or chronic conditions like asthma.

How Is the Test Performed?

A small blood sample is taken from your arm. The blood is sent to a lab where it is analyzed to measure total IgE levels using an immunoassay method.

What Do Results Mean?

Results may be compared to general reference ranges to help determine if IgE levels are elevated or within normal limits. Elevated IgE often suggests an allergic reaction or immune sensitivity.

Reference range

NCBI: NSE 0-17 ng/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

High IgE levels are commonly associated with allergic conditions, such as hay fever, eczema, or food allergies. They may also indicate conditions like asthma, atopic dermatitis, or parasitic infections. Low IgE levels are less commonly significant but could be evaluated in rare cases of immune deficiencies or atypical allergic responses.

Short name

Total IgE (Serum)

Frequently asked questions

What causes elevated IgE levels?
Elevated IgE levels are often due to allergies, asthma, or other allergic diseases. They can also be linked to certain infections, autoimmune conditions, or genetic predispositions.
What if my IgE levels are normal?
Normal IgE levels don’t always mean you don’t have allergies. Other tests or symptoms may be needed to diagnose conditions like food intolerances or environmental sensitivities.
Can IgE levels change over time?
Yes, IgE levels can fluctuate depending on exposure to allergens, underlying health conditions, or treatments like allergy immunotherapy (allergy shots). Regular monitoring may be recommended if you have chronic allergies.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy