Serum or plasma concentration of a substance related to kidney function (e.g., creatinine, urea, or electrolytes measured in a 24-hour urine collection)
This test measures specific substances in your urine over a full day to help assess kidney function, fluid balance, or metabolic processes. It may also detect imbalances in electrolytes, waste products, or other chemicals in your body.
["Understanding how your body processes fluids, waste, and electrolytes over time can help identify kidney or metabolic issues early."]
Key facts at a glance
- LOINC
- 96546-7
- Short code
- Country where dx
- Synonyms
- Country where dx
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your doctor may order this test if they suspect kidney problems, fluid or electrolyte imbalances, or conditions affecting how your body handles waste (like diabetes or certain medications). It can also help monitor chronic conditions or guide treatment plans.
What to Expect Before the Test
You’ll need to collect all urine for 24 hours, starting and ending at the same time (e.g., midnight to midnight). Drink plenty of water to help your kidneys produce urine consistently. Avoid certain medications or foods that might interfere with results, if instructed.
What the Test Measures
This test typically checks for substances like creatinine, urea, sodium, potassium, or other electrolytes, proteins, or markers that reflect kidney function, hydration status, or metabolic health. Results help determine if your kidneys are working properly or if there’s an imbalance in your body’s chemistry.
How the Results Are Used
Your doctor will compare your results to standard ranges to identify any abnormalities. For example, high levels of certain substances might indicate kidney disease, dehydration, or other health concerns. Low levels could signal fluid overload or metabolic issues.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
24-Hour Urine Substance Profile (Qualitative/Quantitative)
Frequently asked questions
What could cause abnormal results?
How long will I need to wait for results?
Can I drink water before or during the 24-hour urine collection?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy