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Antibody Test for SARS-CoV-2 (COVID-19) – Serological Screening

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies in your blood that your immune system produces in response to exposure to the COVID-19 virus. Antibodies can help your body fight off the virus and may indicate past infection.

Quick summary

["This test helps determine if you’ve had exposure to COVID-19, even if you didn’t get sick."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
96738-0
Short code
COVID19LETTER
Synonyms
—
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
role
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

This test measures specific types of antibodies (immunoglobulins) produced by your immune system after exposure to the COVID-19 virus. Antibodies like IgG and IgM are detected to assess immune response timing and potential past infection.

Why Might You Need This Test?

Doctors may recommend this test if you’ve had COVID-19 symptoms, recovered from COVID-19, or been exposed to someone with COVID-19. It can also help track immunity in vaccinated individuals or assess exposure in workplace or community settings.

How Is the Test Performed?

A small blood sample is taken from your arm. The blood is then analyzed in a lab to detect antibodies against the virus. Results are typically available within 24 to 48 hours.

What Are the Possible Results?

Results may show either a positive or negative antibody presence. A positive result suggests your immune system has recognized the virus, while a negative result means no detectable antibodies were found at this time.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Positive results indicate past infection and immunity, which may protect against future illness. However, antibody levels can decline over time, so immunity may not last indefinitely. Negative results mean no detectable antibodies were found, which does not rule out past exposure or immunity. This test is not a replacement for current COVID-19 testing methods like PCR or antigen tests.

Short name

COVID-19 Antibody Test

Frequently asked questions

What Does a Positive Antibody Test Mean?
A positive antibody test means your immune system has likely encountered the COVID-19 virus before, producing antibodies to help fight it. This could indicate past infection, but it does not guarantee long-term immunity.
Can Antibodies Be Used to Confirm Past COVID-19?
Antibody tests can suggest past infection but are not definitive proof. They are often used alongside clinical history and other tests to support a diagnosis of past COVID-19.
How Long Do Antibodies Stay in the Blood?
Antibodies may remain detectable for months or years after infection, but their levels can decrease over time. Some people may no longer have detectable antibodies after a few months.
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Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy