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Cow’s Milk IgG Immunoassay (Serum)

Published: August 9, 2026Updated: August 17, 2026

This test measures the level of Immunoglobulin G (IgG) antibodies your body produces in response to cow’s milk proteins. It helps identify if you may have an allergic reaction or sensitivity to cow’s milk.

Quick summary

["This test checks for cow’s milk antibodies in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
102727-5
Short code
Cow Milk IgG RAST
Synonyms
Cow Milk IgG RAST
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
rast
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

IgG is a type of antibody your immune system makes to fight off infections and foreign substances, including proteins from cow’s milk. This test specifically looks for IgG antibodies that your body creates in response to cow’s milk proteins. These antibodies can indicate a possible allergy or sensitivity, though they are not always a definitive sign of an allergy.

Why Might You Need This Test?

Your healthcare provider may recommend this test if you have symptoms like hives, digestive issues, or other reactions after consuming cow’s milk, or if you’re considering a food elimination diet. It can help determine whether cow’s milk proteins trigger an immune response in your body.

How Is the Test Performed?

A blood sample is taken from a vein in your arm. The sample is then sent to a lab where it is analyzed using an immunoassay method to detect cow’s milk-specific IgG antibodies. The process is quick and typically requires minimal discomfort.

What Are Possible Results?

Results are qualitative (positive or negative) and indicate the presence or absence of cow’s milk-specific IgG antibodies. A positive result suggests your body has produced these antibodies, which may mean you have an immune response to cow’s milk proteins. However, this does not always mean you have an allergy—it could also indicate a tolerance or exposure.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

IgG Against Cow’s Milk (Serum)

Frequently asked questions

How long does it take to get results from this test?
Results from this test are usually available within a few days to a week, depending on the lab’s processing time. Your healthcare provider will discuss the results with you during your follow-up visit.
Can a positive result mean I have a cow’s milk allergy?
A positive result for cow’s milk IgG antibodies suggests your body has mounted an immune response, but it does not definitively confirm a cow’s milk allergy. Allergies are typically diagnosed through a combination of medical history, skin testing, or oral food challenges. IgG antibodies alone are not enough to diagnose an allergy.
What should I do if my test result is positive?
If your test result is positive, discuss your findings with your healthcare provider. They may recommend further testing, such as an allergy skin test or elimination diet, to better understand your reaction to cow’s milk. They can also help you manage symptoms or adjust your diet accordingly.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy