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Total Protein in Serum (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein in your blood serum, which includes proteins like albumin and globulins that help maintain fluid balance, support immunity, and transport nutrients.

Quick summary

["Total protein helps assess overall health, kidney function, and potential nutritional deficiencies."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
57950-8
Short code
Cow Whey IgE/IgE total %
Synonyms
Cow Whey IgE/IgE total %
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for conditions like malnutrition, liver disease, kidney problems, or infections. It can also help monitor treatment responses in certain conditions.

What Does the Result Mean?

Results may be lower than expected if you have malnutrition, kidney disease, or liver problems, or if you’re not absorbing nutrients properly. Higher-than-normal results might suggest dehydration, multiple myeloma, or certain inflammatory conditions.

How Is the Test Performed?

A small blood sample is drawn from a vein, usually in your arm. The serum portion is then analyzed to measure total protein levels using a specialized laboratory technique.

What Are Common Causes of Abnormal Results?

Low protein levels can result from poor diet, chronic illnesses, or conditions that affect protein production or absorption. High protein levels may indicate dehydration, severe infections, or certain blood disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Total protein levels can provide clues about your body’s overall protein status, which is vital for many bodily functions. Low levels may signal underlying health issues that need further investigation, while high levels could point to conditions requiring medical attention.

Short name

Total Protein

Frequently asked questions

What might cause my protein levels to be too low?
Low protein levels can be caused by conditions like chronic kidney disease, liver disease, malnutrition, or certain infections. Your doctor may also check for conditions affecting protein absorption or production, such as celiac disease or severe burns.
What should I do if my protein test results are abnormal?
If your results are outside the expected range, your healthcare provider will discuss them with you and may recommend further tests or adjustments to your treatment plan. They might also suggest lifestyle changes or dietary modifications if needed.
How often should I get this test?
The frequency depends on your health status and any conditions you have. Your doctor will determine how often to check your protein levels based on your individual needs, such as monitoring chronic diseases or managing nutritional health.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy