Skip to content

Paraprotein Detection in Serum/Plasma Using Nucleotide Amplification Probe (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test checks for abnormal protein fragments (paraproteins) in your blood, which may indicate conditions like multiple myeloma or other monoclonal gammopathies.

Quick summary

["This test helps identify unusual protein patterns that could signal serious blood disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
92799-6
Short code
C parap DNA Bld Pos Ql NAA+probe
Synonyms
C parap DNA Bld Pos Ql NAA+probe
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects the presence of abnormal proteins (paraproteins) created by an overactive plasma cell disorder. These proteins are not typically found in healthy blood and may appear in small amounts due to an underlying condition.

Why It’s Done

Your healthcare provider may order this test if you have symptoms like unexplained fatigue, frequent infections, bone pain, or if tests show unusual protein levels in your blood or urine.

How It Works

A small blood sample is taken and analyzed using a specialized probe that detects genetic material linked to paraproteins. The result is qualitative (yes/no) rather than a numeric measurement.

What to Expect

You’ll receive a report indicating whether paraproteins were found. If positive, further testing (like bone marrow biopsy) may be needed to determine the cause.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Frequently asked questions

This test is critical for diagnosing conditions like multiple myeloma, where abnormal plasma cells produce large amounts of paraproteins. Early detection improves treatment options.
This test is not a standalone diagnosis but often used alongside other blood or urine tests to guide further evaluation.
How long will results take?
Results are typically available within 2–5 business days, depending on lab processing times.
Can I fast before this test?
No fasting is required, but inform your provider if you’re on certain medications that may affect bloodwork.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy