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C-peptide (Serum/Plasma, Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of C-peptide, a natural byproduct produced when your body processes insulin. It helps assess how well your pancreas is producing insulin.

Quick summary

["C-peptide helps evaluate insulin production and diabetes management."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
56582-0
Short code
C peptide 10M p chal SerPl-mCnc
Synonyms
C peptide 10M p chal SerPl-mCnc
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why is this test done?

Your doctor may order a C-peptide test to check if your pancreas is making enough insulin, especially if you have diabetes or symptoms like unexplained weight loss, fatigue, or high blood sugar levels. It can also help determine whether insulin is the cause of symptoms or if another issue is present.

How is the test performed?

A small blood sample is taken from a vein in your arm. The blood is sent to a lab where it is processed to measure C-peptide levels. No special preparation is usually needed, but you may be asked to fast for a few hours before the test.

What does the test result mean?

Results are interpreted by your healthcare provider based on your medical history and symptoms. High or low levels may indicate problems with insulin production or diabetes. There is no single reference range provided here as values can vary based on individual health and testing context.

What are the common reasons for testing?

Common reasons include diagnosing type 1 or type 2 diabetes, assessing insulin resistance, evaluating pancreatic function, and monitoring treatment for diabetes or other endocrine conditions.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

C-peptide level

Frequently asked questions

What does a high C-peptide level mean?
A high C-peptide level may indicate that your body is producing insulin naturally, which can sometimes be seen in type 2 diabetes or insulin resistance. It does not always mean you have diabetes, but it may prompt further evaluation.
What does a low C-peptide level mean?
A low C-peptide level often suggests that your pancreas is not producing enough insulin, which is commonly seen in type 1 diabetes or severe insulin deficiency. This can affect how your body regulates blood sugar.
Can diet or fasting affect C-peptide levels?
Yes, diet and fasting can influence C-peptide levels. Fasting can temporarily lower C-peptide levels, so if your test is done during fasting, it may not reflect your normal insulin production levels. Your doctor will consider these factors when interpreting results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy