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C-peptide (Serum) with 15-Minute Postprandial Glucose Measurement

Published: August 9, 2026Updated: August 16, 2026

This test measures C-peptide, a natural byproduct of insulin production, alongside blood glucose levels taken 15 minutes after eating. It helps assess how your pancreas responds to food.

Quick summary

["This test helps track how your body produces insulin after meals and may support diabetes management."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47585-5
Short code
C peptide 15M p Glc SerPl-sCnc
Synonyms
C peptide 15M p Glc SerPl-sCnc
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you have diabetes or are at risk for it to evaluate how well your pancreas produces insulin. It can also help monitor how well your current diabetes treatment is working, especially after meals.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, typically drawn from a vein in your arm. If glucose is measured postprandially, you may be asked to eat a small meal or snack before the blood draw.

What the Results Mean

C-peptide levels help determine if your pancreas is producing insulin normally. Elevated glucose levels after eating may indicate poor insulin function or resistance. Your doctor will interpret these results in the context of your overall health.

Common Causes of Abnormal Results

Low C-peptide levels might suggest insulin overproduction (e.g., from a tumor) or inadequate pancreatic function. High glucose levels after eating could indicate diabetes, metabolic syndrome, or poor meal management.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is critical for diagnosing and managing type 1 and type 2 diabetes, particularly in assessing insulin secretion dynamics. It can also help differentiate between insulin-dependent and insulin-independent conditions, such as gestational diabetes or pancreatic disorders.

Short name

C-peptide + Glucose Check

Frequently asked questions

Will I need to fast before this test?
No fasting is required for the C-peptide portion, but if glucose is measured postprandially, you’ll likely eat a meal or snack beforehand to simulate a real-life scenario.
How long will it take to get my results?
Results are typically available within a few days to a week, depending on your lab’s processing time. Your doctor will contact you with the final interpretation.
Can I take my diabetes medication before this test?
Yes, you can take your usual diabetes medications as scheduled, but inform your doctor if you’re unsure about timing, especially for glucose measurements.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy