C-peptide (Serum/Plasma)
This test measures C-peptide, a small protein produced equally with insulin during digestion. It helps assess how much insulin your pancreas naturally makes.
["C-peptide helps evaluate insulin production and diabetes management."]
Key facts at a glance
- LOINC
- 13038-5
- Short code
- C peptide 30M p chal SerPl-mCnc
- Synonyms
- C peptide 30M p chal SerPl-mCnc
- Category
- coagulation
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 0.8
- Ref high
- 1.2
- Critical range
- — – 5 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 85610
- SNOMED
- 396252006
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Is C-Peptide Used For?
C-peptide testing is primarily used to diagnose and monitor diabetes, particularly Type 1 diabetes, where the pancreas produces little to no insulin. It can also help distinguish between insulin-dependent and insulin-independent diabetes. Additionally, it may be used to evaluate pancreatic function in people with suspected diabetes or other metabolic disorders.
How Is the Test Performed?
A blood sample is drawn from a vein, usually in your arm. The sample is sent to a lab where it is analyzed using an immunoassay method to measure C-peptide levels. No special preparation is typically required, but fasting may be recommended in some cases for certain clinical contexts.
Why Might You Need This Test?
You may need a C-peptide test if your doctor suspects diabetes, especially Type 1 diabetes, or if you have symptoms like excessive thirst, frequent urination, unexplained weight loss, or fatigue. It can also be used to check how well your pancreas is producing insulin, especially in people with diabetes who are taking insulin therapy.
What Do Results Mean?
High C-peptide levels may indicate that your body is producing insulin naturally, which can be useful in diagnosing Type 2 diabetes or distinguishing between different types of diabetes. Low or undetectable levels often suggest Type 1 diabetes or insufficient insulin production. Your doctor will interpret results in the context of your overall health and symptoms.
Reference range
INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A
Inform your healthcare provider if you are taking blood thinners. No special preparation required.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
C-peptide level
Frequently asked questions
Why do I need this test if I already have diabetes?
Can C-peptide test results change over time?
Is there anything I should avoid before the test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy