C-peptide (Serum) Quantitative
This test measures the amount of C-peptide in your blood. C-peptide is a natural substance produced along with insulin when your pancreas releases it to manage blood sugar levels.
["C-peptide helps doctors assess how well your pancreas is producing insulin naturally."]
Key facts at a glance
- LOINC
- 58520-8
- Short code
- C peptide 5M p 1 mg Gc IV SerPl-sCnc
- Synonyms
- C peptide 5M p 1 mg Gc IV SerPl-sCnc
- Category
- coagulation
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 0.8
- Ref high
- 1.2
- Critical range
- — – 5 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 85610
- SNOMED
- 396252006
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Is C-Peptide Used For?
C-peptide is primarily used to evaluate pancreatic function. It helps distinguish between conditions where insulin is produced naturally versus when it is injected or supplemented. For example, it can help identify whether diabetes is caused by insufficient insulin production (type 1 or type 2 diabetes) or other factors like insulin resistance or external insulin use.
Why Might You Need This Test?
Your doctor may order a C-peptide test if you have diabetes symptoms, unexplained blood sugar issues, or if they suspect a problem with how your pancreas produces insulin. It can also be used to monitor treatment effectiveness or rule out conditions like insulinoma (a rare tumor that causes excessive insulin production).
How Is the Test Done?
A blood sample is taken from a vein, usually in your arm. The sample is sent to a lab where it is analyzed to measure the concentration of C-peptide. This test does not require fasting, but your doctor may provide specific instructions.
What Does the Test Result Mean?
Results are interpreted based on your clinical picture rather than a single reference range. High levels may suggest overproduction of insulin (e.g., insulinoma) or recent insulin administration, while low levels may indicate insufficient pancreatic function. Your doctor will discuss findings in the context of your health.
Reference range
INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A
Inform your healthcare provider if you are taking blood thinners. No special preparation required.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
C-peptide level
Frequently asked questions
How long does it take to get my C-peptide results back?
Can I eat or drink before this test?
What are common reasons doctors order a C-peptide test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy