Peptide fragment analysis (C-terminal propeptide of procollagen, serum/plasma)
This test measures specific peptide fragments from collagen proteins in your blood, often used to assess collagen metabolism or detect certain collagen-related conditions.
["This test helps evaluate collagen production or breakdown, which may be important in conditions like fibrotic diseases or connective tissue disorders."]
Key facts at a glance
- LOINC
- 35195-7
- Short code
- C peptide SerPl-msCnc
- Synonyms
- C peptide SerPl-msCnc
- Category
- coagulation
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 0.8
- Ref high
- 1.2
- Critical range
- — – 5 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 85610
- SNOMED
- 396252006
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why Is This Test Done?
Your healthcare provider may order this test if you have symptoms or conditions linked to abnormal collagen metabolism, such as fibrotic lung disease, certain skin disorders, or metabolic bone diseases. It may also be used in research or specialized diagnostic contexts where collagen-related peptides are relevant.
What Does the Test Measure?
The test detects peptide fragments from procollagen, a precursor protein that becomes collagen in your body. These fragments can reflect how well collagen is being processed or if there’s an imbalance in collagen synthesis or breakdown.
Sample Collection and Preparation
A blood sample is drawn from a vein, typically in the arm. The blood is then processed to separate serum or plasma, which is sent to the lab for analysis. This test does not require fasting.
What Are Common Uses?
While less common than other blood tests, this type of analysis may be used in research settings, specialized diagnostics for collagen-related disorders, or to monitor conditions where collagen metabolism is altered.
Reference range
INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A
Inform your healthcare provider if you are taking blood thinners. No special preparation required.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Frequently asked questions
What does this test measure?
How is the result interpreted?
Can this test be done at home?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy