Peptide fragment analysis (C-terminal propeptide of collagen type I)
This test measures a small peptide fragment produced during collagen synthesis, often used in conjunction with other collagen-related studies. It helps assess collagen metabolism or structural integrity in serum/plasma.
["This test may be used to evaluate collagen-related conditions or as part of broader biochemical assessments."]
Key facts at a glance
- LOINC
- 14633-2
- Short code
- C peptide SerPl-sCnc
- Synonyms
- C peptide SerPl-sCnc
- Category
- coagulation
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 0.8
- Ref high
- 1.2
- Critical range
- — – 5 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 85610
- SNOMED
- 396252006
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test detects a specific peptide fragment derived from collagen type I, a structural protein in connective tissues. This fragment is released during normal collagen processing and can be measured in your blood sample. While not a direct measure of collagen levels, it reflects metabolic activity or potential abnormalities in collagen synthesis or degradation.
Why It Might Be Ordered
Your healthcare provider may request this test if you have symptoms or conditions linked to altered collagen metabolism, such as connective tissue disorders, certain metabolic syndromes, or as part of a broader diagnostic evaluation for unexplained biochemical changes.
Common Uses in Clinical Practice
This test is less commonly standalone but may be included in panels assessing collagen-related disorders, metabolic screening, or research studies. It can complement other tests like collagen type I or related protein assays when evaluating systemic collagen involvement.
What to Expect Before the Test
No special preparation is typically required, but you may be asked to fast for 8–12 hours before the draw if your provider specifies. Avoid excessive alcohol or certain medications that could affect blood chemistry. Bring any medications you’re currently taking to your appointment.
Reference range
INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A
Inform your healthcare provider if you are taking blood thinners. No special preparation required.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
C-Peptide (Collagen Type I C-Terminal Fragment)
Frequently asked questions
How might this test result affect my care?
What if my result is outside of normal ranges?
Does this test have any risks or side effects?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy