Peptide C (Propeptide C) in Serum or Plasma
This test measures a specific protein fragment called Peptide C, which is produced during the breakdown of certain blood proteins. It helps assess kidney function and the presence of certain blood disorders.
["Peptide C levels can indicate kidney health and potential blood clotting issues."]
Key facts at a glance
- LOINC
- 58504-2
- Short code
- C peptide sp1 p chal SerPl-mCnc
- Synonyms
- C peptide sp1 p chal SerPl-mCnc
- Category
- coagulation
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 0.8
- Ref high
- 1.2
- Critical range
- — – 5 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 85610
- SNOMED
- 396252006
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why Is This Test Done?
Your healthcare provider may order this test to evaluate kidney function, particularly in conditions like kidney disease or to monitor patients with certain blood disorders. Peptide C is also sometimes checked in people with suspected kidney-related clotting problems or those undergoing dialysis.
What Does This Test Measure?
Peptide C is a marker derived from the breakdown of a protein called C4, which is part of the complement system—a group of proteins in your blood that help fight infections. Elevated levels may suggest kidney damage or certain autoimmune conditions.
How Is This Test Performed?
A blood sample is taken from a vein, usually in your arm. The sample is then sent to a lab for analysis using a specialized immunoassay method to detect Peptide C levels.
What Are Common Results?
Results are typically reported as a mass concentration in the blood. While reference ranges vary by lab, abnormal results may signal underlying health concerns that need further evaluation.
Reference range
INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A
Inform your healthcare provider if you are taking blood thinners. No special preparation required.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Peptide C levels can be elevated in conditions affecting kidney function, such as glomerulonephritis or other inflammatory kidney diseases. It may also be relevant in monitoring patients with certain clotting disorders or those on immunosuppressive therapy. However, further testing and clinical correlation are essential to interpret results accurately.
Short name
Peptide C Level
Frequently asked questions
What does an abnormal Peptide C level mean?
How often should I get this test?
Can diet or medications affect Peptide C levels?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy